IL2 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comIL2 Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > IL2(Gene name) > Human

IL2 (Gene name),

Interleukin-2 (Protein name ), IL2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

IL2;

Protein name:

Interleukin-2(IL-2);

Alternative:

T-cell growth factor(TCGF);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

153

Sequence:

50:

100:

150:

153:

TLT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

147680

Pfam:

PF00715

SMR:

P60568

UniGene:

Hs.89679

KEGG:

hsa:3558

STRING:

9606.ENSP00000226730

String:

P60568

Uniprot:

P60568

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ELISA Kit for Human IL-2

Cat.:

E0073b

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Packing:

96T

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ELISA Kit for Human IL-2

Cat.:

E0073d

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Packing:

96T

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ELISA Kit for Human IL-2

Cat.:

E0073m

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96T

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ELISA Kit for Human IL-2

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ELISA Kit for Human IL-2

Cat.:

E0073r

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96T

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ELISA Kit for Human IL-2

Cat.:

E0073p

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96T

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ELISA Kit for Human IL-2

Cat.:

E0073h

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Packing:

96T

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CLIA Kit for Human IL-2

Cat.:

U0073h

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Packing:

96T

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CLIA Kit for Human IL-2

Cat.:

U0073p

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Packing:

96T

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CLIA Kit for Human IL-2

Cat.:

U0073r

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Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human IL-2

Cat.:

U0073b

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Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human IL-2

Cat.:

U0073d

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Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human IL-2

Cat.:

U0073m

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Packing:

96T

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CLIA Kit for Human IL-2

MSDS:

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Polyclonal Antibody for Human IL-2

Cat.:

P0073Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human IL-2

Cat.:

P0073Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human IL-2

Cat.:

P0073Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human IL-2

Protein for Human IL-2

Cat.:

R0073h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Human IL-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning of interleukin 2 mRNAs from human tonsils."
Maeda S. , Nishino N. , Obaru K. , Mita S. , Nomiyama H. , Shimada K. , Fujimoto K. , Teranishi T. , Hirano T. , Onoue K.
Biochem. Biophys. Res. Commun.115:1040-1047(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Structure and expression of a cloned cDNA for human interleukin-2."
Taniguchi T. , Matsui H. , Fujita T. , Takaoka C. , Kashima N. , Yoshimoto R. , Hamuro J.
Nature302:305-310(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
3.

"Molecular cloning of human interleukin 2 cDNA and its expression in E. coli."
Devos R. , Plaetinck G. , Cheroutre H. , Simons G. , Degrave W. , Tavernier J. , Remaut E. , Fiers W.
Nucleic Acids Res.11:4307-4323(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Structure of the human interleukin 2 gene."
Fujita T. , Takaoka C. , Matsui H. , Taniguchi T.
Proc. Natl. Acad. Sci. U.S.A.80:7437-7441(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"DNA sequence of the 5' flanking region of the human interleukin 2 gene: homologies with adult T-cell leukemia virus."
Holbrook N.J. , Lieber M. , Crabtree G.R.
Nucleic Acids Res.12:5005-5013(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"T-cell growth factor: complete nucleotide sequence and organization of the gene in normal and malignant cells."
Holbrook N.J. , Smith K.A. , Fornace A.J. Jr. , Comeau C.M. , Wiskocil R.L. , Crabtree G.R.
Proc. Natl. Acad. Sci. U.S.A.81:1634-1638(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"Interleukin-2 transcripts in human and rodent brains: possible expression by astrocytes."
Eizenberg O. , Faber-Elman A. , Lotan M. , Schwartz M.
J. Neurochem.64:1928-1936(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
8.

"Sequence of interleukin-2 isolated from human placental poly A+ RNA: possible role in maintenance of fetal allograft."
Chernicky C.L. , Tan H. , Burfeind P. , Ilan J. , Ilan J.
Mol. Reprod. Dev.43:180-186(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Placenta.
9.

SeattleSNPs variation discovery resource
Submitted (2001-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
10.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Blood.
11.

"Organization of the DNA regions flanking the human interleukin 2 gene."
Nishino N. , Obaru K. , Maeda S. , Shimada K. , Onoue K.
Biomed. Res.6:197-205(1985)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-68
12.

"Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells."
Siebenlist U. , Durand D.B. , Bressler P. , Holbrook N.J. , Norris C.A. , Kamoun M. , Kant J.A. , Crabtree G.R.
Mol. Cell. Biol.6:3042-3049(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-69
13.

"Structure-activity relationships of recombinant human interleukin 2."
Weir M.P. , Chaplin M.A. , Wallace D.M. , Dykes C.W. , Hobden A.N.
Biochemistry27:6883-6892(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 21-153
14.

"Amino acid sequence and post-translational modification of human interleukin 2."
Robb R.J. , Kutny R.M. , Panico M. , Morris H.R. , Chowdhry V.
Proc. Natl. Acad. Sci. U.S.A.81:6486-6490(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-153;DISULFIDE BOND;GLYCOSYLATION AT THR-23
15.

"Expression of human interleukin-2 in recombinant baby hamster kidney, Ltk-, and Chinese hamster ovary cells. Structure of O-linked carbohydrate chains and their location within the polypeptide."
Conradt H.S. , Nimtz M. , Dittmar K.E.J. , Lindenmaier W. , Hoppe J. , Hauser H.
J. Biol. Chem.264:17368-17373(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-23
16.

"Three-dimensional structure of interleukin-2."
Brandhuber B.J. , Boone T. , Kenney W.C. , McKay D.B.
Science238:1707-1709(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS)
17.

"Unraveling the structure of IL-2."
Bazan J.F.
Science257:410-412(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COMPARISON OF X-RAY STRUCTURES
18.

McKay D.B.
Science257:412-413(1992)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RESPONSE TO PUBMED:1631562
19.

"Secondary structure of human interleukin 2 from 3D heteronuclear NMR experiments."
Mott H.R. , Driscoll P.C. , Boyd J. , Cooke R.M. , Weir M.P. , Campbell I.D.
Biochemistry31:7741-7744(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
20.

"The interleukin-2 and interleukin-4 receptors studied by molecular modelling."
Bamborough P. , Hedgecock C.J. , Richards W.G.
Structure2:839-851(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING
21.

"Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors."
Wang X. , Rickert M. , Garcia K.C.
Science310:1159-1163(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 21-153 IN COMPLEX WITH IL2RA; IL2RB AND IL2RC
22.

"Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor."
Stauber D.J. , Debler E.W. , Horton P.A. , Smith K.A. , Wilson I.A.
Proc. Natl. Acad. Sci. U.S.A.103:2788-2793(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 21-153 IN COMPLEX WITH IL2RA; IL2RB AND IL2RC;DISULFIDE BOND

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